Endosome dynamics regulated by a Rho protein.
basic_science · Level V
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- Record sourced from PubMed, PMID 8945468.
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Abstract
Vesicular transport is a dynamic process that requires coordinated interactions between membrane and cytoskeleton. The mechanisms and molecules integrating these interactions are unclear. A Rho protein, RhoD, might provide a molecular link between membrane traffic and the cytoskeleton. Activated RhoD causes rearrangements of the actin cytoskeleton and cell surface, and governs early endosome motility and distribution.
Medical subject headings
- Endosomes
- GTP Phosphohydrolases
- Proteins
- rho GTP-Binding Proteins