Cutaneous lymphocytic vasculitis in acute myeloid leukaemia.

Farrell, A M; Gooptu, C; Woodrow, D; Costello, C; Bunker, C B; Cream, J J · Br J Dermatol · 1996

case_report · Level V

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Abstract

We report a 63-year-old woman who presented with an 8-week history of widespread indurated, purpuric lesions associated with weight loss of 7 kg and several episodes of epistaxis. A skin biopsy demonstrated a lymphocytic vasculitis with haemorrhage and parakeratosis. A blood film and bone marrow examination showed features of a myelodysplastic syndrome in transformation to acute myeloid leukaemia. Leucocytoclastic vasculitis and polyarteritis nodosa occur in association with acute myeloid leukaemia, but the association with lymphocytic vasculitis is new.

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