Acute renal failure due to sulphadiazine crystalluria in AIDS patients.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 8949595.
- Also identified by PMC identifier 2398565.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
We report two AIDS patients who developed acute renal failure while receiving sulphadiazine for cerebral toxoplasmosis. Renal ultrasound revealed diffuse bilateral echogenic shadowing material. 'Sheaves of wheat' crystals, typical of sulphadiazine crystalluria, were present in the urine. One patient required a percutaneous nephrostomy. Hydration and urine alkalinisation resulted in rapid improvement of renal function and ultrasonographic findings. Sulphadiazine-induced crystalluria and acute renal failure is increasingly frequent. Awareness of its existence may lead to prevention and early conservative treatment.
Medical subject headings
- AIDS-Related Opportunistic Infections
- Acute Kidney Injury
- Anti-Infective Agents
- Sulfadiazine
- Toxoplasmosis, Cerebral