Host factors and the pathogenesis of HIV-induced disease.

Fauci, A S · Nature · 1996

review · Level V

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Abstract

The level of human immunodeficiency virus (HIV) replication in patients reflects a balance between stimulatory and inhibitory host factors (particularly endogenous cytokines). New information concerning the cellular co-receptors for HIV and the cellular tropism of different strains of virus will advance our understanding of HIV-induced pathogenesis and suggests new therapeutic and preventive strategies.

Medical subject headings