Successful treatment of non-familial haemophagocytic lymphohistiocytosis with interferon and gammaglobulin.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 8957958.
- Also identified by PMC identifier 1511773.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Two cases of non-familial haemophagocytic lymphohistiocytosis (HLH) are presented in which treatment with interferon alfa and gammaglobulin was associated with complete clinical remission. In one case, serological evidence of recent Epstein-Barr virus infection was found. Natural killer cell activity was within normal limits in both children, compatible with a secondary form of HLH. The combination of interferon alfa and intravenous gammaglobulin requires further evaluation in the treatment of non-familial HLH.
Medical subject headings
- Histiocytosis, Non-Langerhans-Cell
- Immunization, Passive
- Interferon-alpha