Symmetry and the energy landscapes of biomolecules.
basic_science · Level V
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- Record sourced from PubMed, PMID 8962034.
- Also identified by PMC identifier 34469.
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Abstract
The role of symmetry in the folding of proteins is discussed using energy landscape theory. An analytical argument shows it is much easier to find sequences with funneled energy landscape capable of fast folding if the structure is symmetric. The analogy with phase transitions of small clusters with magic numbers is discussed.
Medical subject headings
- Evolution, Molecular
- Protein Conformation
- Proteins