Biosynthesis of vitamin B12: factor IV, a new intermediate in the anaerobic pathway.
basic_science · Level V
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- Record sourced from PubMed, PMID 8962047.
- Also identified by PMC identifier 26128.
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Abstract
The structure of a novel tetradehydrocorrin, factor IV, isolated from Propionibacterium shermanii has been established by multidimensional NMR spectroscopy. Incorporation of radiolabeled factor IV into cobyrinic acid established the biointermediacy of this cobalt complex, whose structure has implications for the mechanisms of the anaerobic pathway to B12.
Medical subject headings
- Calcium
- Propionibacterium
- Vitamin B 12