Proton long-range migration along protein monolayers and its consequences on membrane coupling.

Gabriel, B; Teissié, J · Proc Natl Acad Sci U S A · 1996

basic_science · Level V

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Abstract

It has been shown with lipid layers and more recently with purple membranes that protons have slow surface-to-bulk transfer. This results in long-range proton lateral conduction along membranes. We report here that such lateral transfer can take place along a pure protein film. It is strongly controlled by the packing. Subtle reorganizations of the protein-protein contact can be biological switches between interfacial and delocalized proton pathways between sources and sinks.

Medical subject headings