Development of primary hypothyroidism with antithyroglobulin, antiperoxidase, and blocking-type thyrotropin receptor antibodies after radiation therapy for neuroblastoma.
case_report · Level V
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Abstract
We describe a girl with hypothyroidism and blocking-type thyrotropin receptor antibodies that developed after chemotherapy and irradiation of the neck region for neuroblastoma. Results of thyroid studies before treatment were normal. Twenty months after completion of treatment, the girl had hypothyroidism with high titers of blocking-type thyrotropin receptor antibodies, antithyroglobulin, and antiperoxidase antibodies.
Medical subject headings
- Antibodies
- Autoimmune Diseases
- Head and Neck Neoplasms
- Hypoparathyroidism
- Neuroblastoma
- Peroxidase
- Radiotherapy
- Receptors, Thyrotropin
- Thyroglobulin