Continuous infusion of methylene blue for septic shock.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 8977944.
- Also identified by PMC identifier 2398584.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Nitric oxide has been determined to be a potential mediator of the haemodynamic changes associated with sepsis. The haemodynamic eects of nitric oxide can be partially antagonised by methylene blue, through inhibition of the enzyme, guanylate cyclase. The case report presented here demonstrates a beneficial haemodynamic eect of continuous infusion of methylene blue during sepsis. These findings could be extrapolated to other patients or prompt additional research.
Medical subject headings
- Antidotes
- Enterococcus faecium
- Gram-Positive Bacterial Infections
- Methylene Blue
- Shock, Septic