Lung transplantation for alpha 1-antitrypsin deficiency emphysema.

Trulock, E P · Chest · 1996

review · Level V

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Abstract

Lung transplantation is an option for appropriately selected patients with end-stage emphysema caused by alpha 1-antitrypsin deficiency. The functional results have been excellent after single or bilateral lung transplantation, and the medium-term survival results have been good. However, the role of alpha 1-antitrypsin replacement therapy after lung transplantation remains uncertain, and further investigation is needed.

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