Increases in rates of resistance to trimethoprim.
review · Level V
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Abstract
Trimethoprim alone or in combination with a sulfonamide is an effective and relatively inexpensive antibacterial medication. However, a dramatic increase in the rate of resistance to trimethoprim along with high-level resistance to sulfonamides has been seen during the past two decades. The mechanisms of resistance show a remarkable evolutionary adaptation.
Medical subject headings
- Anti-Infective Agents, Urinary
- Sulfonamides
- Trimethoprim
- Trimethoprim Resistance
- Trimethoprim, Sulfamethoxazole Drug Combination