Acute hepatitis and drug-related lupus induced by minocycline treatment.

Golstein, P E; Deviere, J; Cremer, M · Am J Gastroenterol · 1997

case_report · Level V

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Abstract

Minocycline is widely prescribed for long-term treatment in acne. Major side effects are rare and include hepatitis and drug-related lupus. Hepatitis can be early and acute or late and chronic, whereas lupus presents as a tardive and insidious disease. We report a case of minocycline-induced lupus initially presenting as acute hepatitis, evolving to chronic cytolysis, in a young man treated for facial acne.

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