Radiation induced intracranial leiomyosarcoma: its histopathological features.

Niwa, J; Hashi, K; Minase, T · Acta Neurochir (Wien) · 1996

case_report · Level V

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Abstract

This is a case of intracranial sarcoma which was recognized 23 years after irradiation therapy for pituitary adenoma. Four operations were performed because of recurrences with a short interval between each operation. Immunohistochemically, the tumour cells were stained for smooth muscle actin, human muscle actin and vimentin. It was verified as a leiomyosarcoma. This report is the first case of intracranial leiomyosarcoma associated with radiation therapy in pituitary adenoma.

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