Esophageal carcinoma presenting with nephrotic syndrome: association with anti-neutrophil cytoplasmic antibody.

Yedidag, A; Zikos, D; Spargo, B; MacEntee, P; Berkelhammer, C · Am J Gastroenterol · 1997

case_report · Level V

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Abstract

Malignancy is a cause of membranous glomerulonephritis. We report a patient with an otherwise asymptomatic squamous cell carcinoma of the esophagus whose presenting manifestation was membranous glomerulonephritis and nephrotic syndrome. Perinuclear anti-neutrophil cytoplasmic antibody was positive. This is the first reported case of perinuclear anti-neutrophil cytoplasmic antibody associated with paraneoplastic glomerulonephritis and nephrotic syndrome due to esophageal squamous cell carcinoma.

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