The role of azole antifungal agents for systemic antifungal therapy.

Cleve Clin J Med · 1997

review · Level V

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Abstract

Although amphotericin B remains the cornerstone of antifungal drug therapy, fluconazole and itraconazole have been found useful for long-term maintenance or prophylactic regimens. This article reviews characteristics of fluconazole and itraconazole and compares them with ketoconazole and amphotericin B.