Antiperinuclear factors are present in polyarthritis before ACR criteria for rheumatoid arthritis are fulfilled.
prospective_cohort · Level II
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- Record sourced from PubMed, PMID 9068286.
- Also identified by PMC identifier 1752319.
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Abstract
To show that antiperinuclear factor (APF) may be useful for the diagnosis of rheumatoid arthritis at a time when the American College of Rheumatology (ACR) criteria are not yet fulfilled. Testing for APF-IgG (1:100 threshold) and rheumatoid factors (RF) was done in 60 patients with polyarthritis of recent onset during a three year follow up. At the end of the study, 21/40 rheumatoid arthritis were positive for RF and 31/40 for APF, including 18/40 cases (45%) in which ACR criteria were not yet fulfilled. APF are useful in the diagnosis of early rheumatoid arthritis.
Medical subject headings
- Antibodies, Antinuclear
- Arthritis, Rheumatoid