Relationship between HLA-C locus and restenosis after coronary artery balloon angioplasty.
cross_sectional · Level IV
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Abstract
To determine the relationship between human leukocyte antigen (HLA) loci and restenosis after percutaneous transluminal coronary angioplasty (PTCA). Cross-sectional study in patients treated by PTCA at Juntendo University Hospital, Tokyo, Japan. A total of 65 patients (58 males and 7 females) with coronary artery stenosis who were consecutively selected between October 1994 and June 1995. Significant relationships between the restenosis and the HLA-Cw1. Among HLA-C locus, Cw1 was negatively related to restenosis (multivariate adjusted odds ratio, 0.19; 95% confidence interval, 0.06-0.63; P=.007). In HLA typing, Cw1 may be a useful marker for the prediction of restenosis after PTCA.
Medical subject headings
- Angioplasty, Balloon, Coronary
- Coronary Disease
- HLA-C Antigens