Wound healing following radiation therapy: a review.
review · Level V
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- Record sourced from PubMed, PMID 9106919.
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Abstract
Radiation therapy may interrupt normal wound healing mechanisms. Changes in vasculature, effects on fibroblasts, and varying levels of regulatory growth factors result in the potential for altered wound healing whether radiation is given before or after surgery. Surgical factors, such as incision size, as well as radiation parameters, including dose and fractionation, are important considerations in developing overall treatment plans. Experience suggests that certain practical measures may diminish the risk of morbidity, and investigations are ongoing.
Medical subject headings
- Postoperative Complications
- Skin
- Wound Healing