Microbial pathogenesis: genomics and beyond.
review · Level V
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Abstract
The growing number of complete microbial genome sequences provides a powerful tool for studying the biology of microorganisms. In combination with assays for function, genomic-based approaches can facilitate efficient and directed research strategies to elucidate mechanisms of bacterial pathogenicity. As genomic information accrues, the challenge remains to construct a picture of the biology that accurately reflects how individual genes collaborate to create the complex world of microbial specialization.
Medical subject headings
- Bacteria
- Genome, Bacterial
- Virulence