Cryopreservation of ovarian tissue. Potential "reproductive insurance" for women at risk of early ovarian failure.
basic_science · Level V
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Abstract
Cryopreservation of ovarian tissue is a potential alternative or addition to cryopreservation of embryos or oocytes for sustaining fertility in women at risk of premature ovarian failure. Grafts of cryopreserved ovarian tissue have resulted in live-born mice and sheep. While human applications are in their infancy, frozen human ovarian tissue grafted to the kidney capsules of immunodeficient mice has produced normally developing ovarian follicles.