Pleomorphic medium-sized T-cell lymphoma following Hodgkin's disease (nodular sclerosis type).

Gaulier, A; Teillet, F; Davi, F; Couturier, J; Laye, S; Raphael, M · Arch Pathol Lab Med · 1997

case_report · Level V

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Abstract

We describe a 32-year-old woman who presented with Hodgkin's disease, nodular sclerosis type II, subtype I, which necessitated several treatments over 11 years. The patient then developed pleomorphic, medium-sized T-cell lymphoma, which had a fatal outcome within 13 months. The role of radiotherapy, splenectomy, and chemotherapy in second tumor induction is compared with other sequential T-cell lymphomas. The significance of rare Epstein-Barr virus-infected cells during the T-cell lymphoma extension is discussed.

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