Gel microdrop technology for rapid isolation of rare and high producer cells.

Weaver, J C; McGrath, P; Adams, S · Nat Med · 1997

basic_science · Level V

Where this comes from

Abstract

Secreted proteins are a therapeutic cornerstone of the biotechnology industry, and numerous recombinant products, including human growth hormone, human erythropoietin and granulocyte-colony stimulating factor, are now widely prescribed. In addition to bioprocessing applications, GMD technology should benefit the emerging fields of cellular and gene therapy. The ability to assess rapidly and precisely the productivity of cells for ex vivo cell screening and expansion is a unique approach with numerous research and therapeutic uses.

Medical subject headings