Antibiotic prophylaxis in ultrasound guided transrectal prostate biopsy.

Sieber, P R; Rommel, F M; Agusta, V E; Breslin, J A; Huffnagle, H W; Harpster, L E · J Urol · 1997

retrospective_cohort · Level III

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Abstract

A retrospective review of a large group of transrectal ultrasound guided biopsies was performed to determine the symptomatic urinary tract infection rate associated with a consistent and defined antibiotic prophylaxis regimen. A total of 4,439 biopsies was performed using an 18 gauge needle with ultrasound guidance. Patients were treated with 500 mg. ciprofloxacin twice daily for 8 doses beginning the day before biopsy. Of 5 symptomatic urinary tract infections noted 3 were complicated. These data demonstrate the low infection rate associated with this prophylaxis regimen.

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