Use of sucrose as a treatment for infant colic.

Markestad, T · Arch Dis Child · 1997

rct · Level II

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Abstract

To examine if sucrose has an analgesic effect on infant colic. Nineteen infants with typical infant colic were given 2 ml of 12% sucrose or distilled water when crying, in a double blind double crossover study. The effect was measured by parents' score. Twelve improved specifically on sucrose and one on placebo (p < 0.01). Five showed a non-specific improvement. Sucrose has a significant ameliorating effect on infant colic.

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