Antimuscle and anti-CNS circulating antibodies in chronic fatigue syndrome.
case_control · Level III
Where this comes from
- Record sourced from PubMed, PMID 9191795.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Chronic fatigue syndrome (CFS) patients suffer from disabling physical and mental fatigue. Circulating autoimmune antibodies may produce symptoms of muscular fatigue by reacting with acetylcholine receptors or calcium binding channels. They can also produce mental status changes by reacting with central nervous system (CNS) antigens. We thoroughly investigated the presence of circulating antimuscle and anti-CNS antibodies in 10 CFS patients and 10 controls. We were unable to detect any pathogenic antibodies.
Medical subject headings
- Autoantibodies
- Central Nervous System
- Fatigue Syndrome, Chronic
- Muscle, Skeletal