Mosaicism for trisomy 3q arising from an unbalanced, de novo t(3;15).
case_report · Level V
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- Record sourced from PubMed, PMID 9192276.
- Also identified by PMC identifier 1050979.
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Abstract
We report on a 2 1/2 year old girl who is dysmorphic, developmentally delayed, and mosaic for an unbalanced, de novo translocation between chromosomes 3 and 15. The karyotype from peripheral blood lymphocytes is 46,XX (50) and the karyotype from skin fibroblasts is 46,XX (28)/46,XX,der(15)t(3;15)(q11;p11) (23). The mechanism for the generation of this unbalanced, de novo translocation is discussed.
Medical subject headings
- Abnormalities, Multiple
- Chromosomes, Human, Pair 15
- Chromosomes, Human, Pair 3
- Mosaicism
- Translocation, Genetic
- Trisomy