Azathioprine-induced lymphoma manifesting as fulminant hepatic failure.
case_report · Level V
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Abstract
Azathioprine and rheumatoid arthritis are known to be associated with an increased risk of the development of non-Hodgkin's lymphoma; however, the manifestation of fulminant hepatic failure is extremely uncommon in patients with non-Hodgkin's lymphoma. In this article, we describe a patient with rheumatoid arthritis who was taking azathioprine, in whom fulminant hepatic failure occurred because of massive lymphomatous infiltration of the liver.
Medical subject headings
- Antirheumatic Agents
- Azathioprine
- Chemical and Drug Induced Liver Injury
- Liver Neoplasms
- Lymphoma, Large-Cell, Anaplastic