Plasma TGFbeta level in rats after hemithoracic irradiation.

Vujaskovic, Z; Down, J D; van Waarde, M A; van Assen, A J; Szabo, B G; Konings, A W · Radiother Oncol · 1997

basic_science · Level V

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Abstract

Changes in TGF-beta plasma levels were observed 18 weeks after hemithoracic irradiation in rats. This coincides with an increase in the breathing frequency. being most pronounced between 22 and 28 weeks after irradiation. The correlation suggests a potential role of the circulating TGF-beta in the monitoring of localized radiation-induced lung injury.

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