Botulinum toxin increases tearing in patients with Sjögren's syndrome: a preliminary report.
case_report · Level V
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- Record sourced from PubMed, PMID 9292815.
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Abstract
Three patients with Sjögren's syndrome (SS) who had severe xerophthalmia and blepharospasm received botulinum toxin injections for the treatment of their blepharospasm. They had a remarkable increase in tearing, measured by Schirmer's test, and a decrease in signs and symptoms of dry eyes after botulinum toxin injection periorbitally for blepharospasm. The mechanism for this increased tearing is unclear, but suggests a potential treatment for patients with severe xerophthalmia with SS.
Medical subject headings
- Anti-Dyskinesia Agents
- Botulinum Toxins
- Sjogren's Syndrome
- Tears