Interferon-alpha associated arthritis.
case_report · Level V
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- Record sourced from PubMed, PMID 9292816.
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Abstract
We describe a patient who developed progressive inflammatory polyarthritis after treatment with interferon-alpha (IFN-alpha) for chronic hepatitis C infection. Rechallenge with the drug caused worsening of the arthritis, but withdrawal did not result in remission. Preexisting autoantibodies and HLA-DR4 were detected in this serum and are thought to be relevant in the etiology of IFN-alpha associated autoimmune disease.
Medical subject headings
- Antiviral Agents
- Arthritis
- Interferon-alpha