Cerebral primitive neuro-ectodermal tumour following treatment of a unilateral retinoblastoma.
case_report · Level V
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Abstract
Cerebral primitive neuro-ectodermal tumour (PNET) occurring as a second primary malignancy in childhood is exceedingly rare. We present a 7-year-old boy who developed a proven supratentorial PNET five years after enucleation and radio-/chemotherapy for a sporadic, unilateral retinoblastoma with optic nerve invasion. The association with this malignant eye disease as well as the effect of irradiation and multi-agent chemotherapy on second tumour induction are evaluated.
Medical subject headings
- Neoplasms, Second Primary
- Neuroectodermal Tumors, Primitive
- Postoperative Complications
- Retinal Neoplasms
- Retinoblastoma
- Supratentorial Neoplasms