Concomitant administration of sodium dichloroacetate and vitamin B1 for lactic acidemia in children with MELAS syndrome.

Kuroda, Y; Ito, M; Naito, E; Yokota, I; Matsuda, J; Saijo, T; Kondo, S; Yoneda, Y et al. · J Pediatr · 1997

case_report · Level V

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Abstract

Myoclonic seizures, intractable abdominal pain, and headaches resolved during the concomitant administration of sodium dichloroacetate and vita min B1 in two Japanese siblings with the MELAS syndrome (mitochondrial myopathy, encephalopathy, lactic acidosis and strokelike syndrome).

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