Diagnostic difficulties in periodic Cushing's syndrome.
case_report · Level V
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- Record sourced from PubMed, PMID 9338031.
- Also identified by PMC identifier 2431411.
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Abstract
A 22-year-old black woman presented with symptoms suggestive of Cushing's syndrome three years after chemotherapy for a presumed teratoma with cervical lymphadenopathy. Initially, the absence of clinical signs and the demonstration of two normal 24 h urinary free cortisols appeared to exclude the diagnosis, but an ectopic adrenocorticotropin-producing thymic carcinoid was subsequently removed surgically. Cushing's syndrome due to ectopic adrenocorticotropin production can be difficult to diagnose, particularly if there is periodic hormonogenesis.
Medical subject headings
- Adrenocorticotropic Hormone
- Carcinoid Tumor
- Cushing Syndrome
- Periodicity
- Thoracic Neoplasms
- Thymoma