Multiorgan dysfunction and disseminated intravascular coagulation in children receiving lamotrigine and valproic acid.
case_report · Level V
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- Record sourced from PubMed, PMID 9371937.
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Abstract
Two children developed multiorgan dysfunction with disseminated intravascular coagulation 9 days after lamotrigine was added to their antiepileptic therapy, which included valproic acid. During the episodes, rhabdomyolysis was detected in one of them, while being seizure-free, suggesting that this adverse reaction may involve muscular tissue.
Medical subject headings
- Anticonvulsants
- Disseminated Intravascular Coagulation
- Multiple Organ Failure
- Triazines
- Valproic Acid