Ifosfamide-induced alteration of technetium-99m-DMSA renal parenchymal imaging.

Morrison, S C; O'Donnell, J K · J Nucl Med · 1997

case_report · Level V

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Abstract

Renal cortical imaging with 99mTc-dimercaptosuccinic acid (DMSA) has become the imaging test of choice for the diagnosis of acute pyelonephritis. An unusual uptake pattern was observed in a child receiving chemotherapy for a bladder rhabdomyosarcoma. Chemotherapy from ifosfamide produces a specific pattern of injury to the renal tubule that alters uptake of DMSA.

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