Treatment of methanol poisoning with intravenous 4-methylpyrazole.
case_report · Level V
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Abstract
Treatment of human methanol poisoning with the alcohol dehydrogenase inhibitor, 4-methylpyrazole (fomepizole), has not been previously described. We report the clinical and toxicokinetic data of a patient with methanol poisoning who was treated with fomepizole. Formic acid levels remained undetectable during fomepizole treatment, the toxic effects of methanol were prevented, and the patient made a full recovery.
Medical subject headings
- Alcohol Dehydrogenase
- Enzyme Inhibitors
- Methanol
- Pyrazoles