Nondispersive infrared spectrometry: a new method for the detection of Helicobacter pylori infection with the 13C-urea breath test.
other · Level V
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Abstract
Nondispersive infrared spectrometry (NDIRS) was used to detect Helicobacter pylori infection with the 13C-urea breath test. The results were compared with those of standard isotope ratio mass spectrometry (IRMS). Both methods accurately distinguished between H. pylori-positive and H. pylori-negative individuals. The results demonstrate that NDIRS technology is accurate and therefore of equal value to standard IRMS for detection of H. pylori infection. It can be recommended for routine clinical application. As NDIRS technology is much cheaper than current IRMS machines, we consider the new method extremely useful for clinical applications.
Medical subject headings
- Breath Tests
- Helicobacter Infections
- Helicobacter pylori
- Spectrophotometry, Infrared
- Urea