Seasonal cyclothymia to seasonal bipolar affective disorder: a double switch after stroke.

Kumar, S; Jacobson, R R; Sathananthan, K · J Neurol Neurosurg Psychiatry · 1997

case_report · Level V

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Abstract

The appearance of bipolar affective disorder after stroke depends on the presence of two factors: a predisposing factor of either genetic loading or subcortical atrophy, and a lesion of specific corticolimbic pathways involving the right hemisphere. Whether cyclothymia and seasonal affective disorder further predispose to poststroke affective disorder is not clear. A case is described which highlights these issues. The aetiological factors, pathophysiology, and diagnosis are discussed.

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