Acute retinal necrosis late in the second trimester.

Shiraki, K; Moriwaki, M; Ataka, S; Henmi, K; Miki, T; Kanaoka, Y · Am J Ophthalmol · 1998

case_report · Level V

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Abstract

To report treatment of a patient with acute retinal necrosis during pregnancy. A 24-year-old woman in her twenty-third week of gestation was diagnosed with acute retinal necrosis. A combination of acyclovir and interferon therapy was started at 25 weeks. Pars plana vitrectomy was performed during the 26th week of gestation. The necrotizing retina became gliotic within 3 weeks of surgery. The patient's visual acuity improved to LE, 20/40. A healthy baby was delivered at 39 weeks of gestation. Combination therapy of acyclovir and interferon followed by surgery partially restored the patient's vision without affecting fetal development.

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