Interferon treatment for corneolimbal squamous dysplasia.
case_report · Level V
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- Record sourced from PubMed, PMID 9437331.
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Abstract
To report a patient with corneolimbal squamous dysplasia successfully treated with interferon therapy. A 78-year-old man had a gelatinous and vascularized lesion involving the left cornea and adjacent limbus. Impression cytology studied with periodic acid--Schiff-hematoxylin stain disclosed severe squamous dysplasia. Topical instillation and subconjunctival injection of interferon alpha-2b was instituted. The gelatinous tumor mass involving the cornea and adjacent limbus completely resolved 2 months after interferon treatment. He showed no sign of recurrence during the 10-month follow-up. Interferon therapy may be a therapeutic alternative for treating corneolimbal squamous dysplasia.
Medical subject headings
- Antineoplastic Agents
- Carcinoma in Situ
- Corneal Diseases
- Eye Neoplasms
- Interferon-alpha