Considerations in optimizing radiation therapy for non-small cell lung cancer.

Greenberger, J S; Bahri, S; Jett, J; Belani, C; Kalend, A; Epperly, M · Chest · 1998

review · Level V

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Abstract

Irradiation therapy for lung cancer is mostly restricted to conventional methods. To improve therapeutic ratio, we have combined a treatment planning and a gene therapy approach. Three-dimensional conformal radiotherapy is described as carried out by methods of gene therapy for radiation protection using the manganese-superoxide-dismutase transgene delivered by inhalation gene transfer. These methods may improve therapeutic outcomes in lung cancer.

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