Microsporidial keratoconjunctivitis in a patient without human immunodeficiency virus infection.

Silverstein, B E; Cunningham, E T; Margolis, T P; Cevallos, V; Wong, I G · Am J Ophthalmol · 1997

case_report · Level V

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Abstract

To describe a case of microsporidial keratoconjunctivitis in a patient without human immunodeficiency virus (HIV) infection. Case report. An epithelial corneal scraping from a woman with chronic bilateral keratoconjunctivitis was evaluated by Giemsa stain. Giemsa stain of an epithelial corneal scraping disclosed intracellular and extracellular spores characteristic of microsporidia. An HIV enzyme-linked immunosorbent assay (ELISA) test was negative. The signs and symptoms of the bilateral keratoconjunctivitis resolved after treatment with albendazole. Microsporidia may cause a chronic epithelial keratoconjunctivitis in the absence of HIV infection.

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