Bilateral renal vein thrombosis and venous sinus thrombosis in a neonate with factor V mutation (FV Leiden).
case_report · Level V
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- Record sourced from PubMed, PMID 9470020.
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Abstract
Bilateral renal vein thrombosis and venous sinus thrombosis were diagnosed within 3 weeks of birth in a full-term neonate. Heterozygosity for a factor V mutation leading to resistance against the anticoagulatory properties of activated protein C was found. Heparin therapy led to resolution of the thrombotic manifestations. With long-term oral anticoagulation, no relapse or other thrombotic event occurred during infancy.
Medical subject headings
- Blood Coagulation Disorders
- Factor V
- Intracranial Embolism and Thrombosis
- Mutation
- Renal Veins
- Thrombosis