The use of heparinase to neutralize residual heparin in blood samples drawn through pediatric indwelling central venous catheters.
case_series · Level IV
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- Record sourced from PubMed, PMID 9470022.
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Abstract
Routine-coagulation screening is unreliable if obtained through a previously heparinized central venous catheter. Screening tests were performed on 14 paired peripheral and central venous catheter samples without and with heparinase. The heparinase treated central venous catheter samples correlated well with the peripheral samples and can be used to atraumatically screen for hemostatic abnormalities.
Medical subject headings
- Blood Coagulation Tests
- Catheterization, Central Venous
- Catheters, Indwelling
- Hemostasis
- Heparin
- Heparin Lyase