Bath-PUVA therapy in three patients with scleredema adultorum.
case_report · Level V
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- Record sourced from PubMed, PMID 9486680.
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Abstract
Scleredema adultorum (SA) is a rare connective tissue disorder for which no treatment has proven to be effective. Our purpose was to determine the effect of bath-PUVA therapy on SA. Three patients were treated. Clinical evaluation of skin induration and thickness as well as ultrasonography were performed at baseline and after treatment. All three patients showed substantial clinical improvement with bath-PUVA therapy (median of 59 treatments and a cumulative UVA dose of 245.7 J/cm2). Ultrasonography showed significant reduction in both skin thickness and density. Bath-PUVA therapy appears to be effective in the treatment of SA.
Medical subject headings
- PUVA Therapy
- Scleredema Adultorum