Mycosis fungoides with focal segmental glomerular sclerosis and nephrotic syndrome.

Cather, J C; Jackow, C; Yegge, J; Hagemeister, F; Duvic, M · J Am Acad Dermatol · 1998

case_report · Level V

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Abstract

Cutaneous T-cell lymphoma includes mycosis fungoides and the leukemic variant, Sézary syndrome. We report the first two cases of focal segmental glomerulosclerosis in patients with cutaneous T-cell lymphoma, with nephrotic range proteinuria and review the literature on renal disease coexisting with cutaneous T-cell lymphoma. We hypothesize that glomerular injury in cutaneous T-cell lymphoma may be related to interleukin-2.

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