Aquadynia: noradrenergic pain induced by bathing and responsive to clonidine.
case_report · Level V
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Abstract
We describe two women in whom bathing was regularly followed by intense, widespread burning pain that lasted 15 to 45 minutes, which we term aquadynia. This water-induced pain was not caused by any skin or systemic diseases. We view it as a type of noradrenergic pain induced by contact with water, because it can be blocked with clonidine or propranolol. It appears to be an extension of the phenomenon of aquagenic pruritus, which we have also found to respond to clonidine or propranolol.
Medical subject headings
- Adrenergic alpha-Agonists
- Baths
- Clonidine
- Norepinephrine
- Pain
- Receptors, Adrenergic