Early infection and subsequent insulin dependent diabetes.

Gibbon, C; Smith, T; Egger, P; Betts, P; Phillips, D · Arch Dis Child · 1997

case_control · Level III

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Abstract

In a study of 58 children under the age of 16 with insulin dependent diabetes (IDDM) and 172 matched non-diabetic controls, infection during the first year of life was associated with a reduction in diabetes risk (odds ratio 0.81, 95% confidence interval 0.67 to 0.98, per infective episode). Decreased exposure to common infections during infancy may be linked with subsequent IDDM.

Medical subject headings