Radiation following chemotherapy for mediastinal Hodgkin's disease: the outcome of various doses for bulky tumors.
retrospective_cohort · Level III
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Abstract
Twenty-one patients with bulky mediastinal disease responding to chemotherapy received consolidation with low-dose mediastinal radiation (19.8-25.2 Gy). Their 5-year mediastinal failure rate (10%) was equivalent to that of 10 similar patients who received higher doses of 30-44 Gy (20%). Low-dose radiation may be appropriate for these patients. Prospective studies are required to verify these findings.
Medical subject headings
- Antineoplastic Agents
- Hodgkin Disease
- Mediastinal Neoplasms